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Description

How We Got Here: A Short Field History Understanding why one of these peptides has robust human data and the other does not requires a little history, because the two molecules were developed to answer different questions in different eras

How They Work + What To Expect Understanding how they work is fundamental to long-term success

Relamorelin (RM-131), a modified ghrelin peptide, was studied in phase 2 trials for diabetic gastroparesis, and macimorelin, a non-peptidyl GHS-R1a agonist, received FDA approval in December 2017 under the brand name Macrilen for the diagnosis of adult growth hormone deficiency, marking the first FDA-approved compound in the ghrelin receptor agonist class