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As a control, we performed the same experiment on cKD-ABCB7/ SDHB-HA parasites at 6-day ATc growth, and saw no decrease in SDHB-HA signal (S4L Fig), indicating the decrease is specific for ABCE1 and does not reflect a general proteolysis due to a loss of viability, and is consistent with the parasites remaining viable for an extended period upon ABCB7 depletion (Fig

References Lawn JE, Cousens S, Zupan J (2005) 4 million neonatal deaths: when

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(2014) demonstrated that vitamin D3 supports decreased IgE-dependent mast cell activation by reducing degranulation and curtailing the release of inflammatory mediators, including histamine and cytokines

10.1039/C9FO02845E 64

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