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The skin is chronically exposed to both endogenous and environmental pro-oxidants leading to the production of ROS.[] ROS leads to lipid peroxidation, which is considered as the hallmark of oxidative stress in body.[] Malondialdehyde (MDA) is considered as the end product of lipid peroxidation and MDA levels is directly proportional to the oxidative stress.[] The most important antioxidants present in human body include superoxide dismutase, glutathione peroxidase, and catalase.[] Glutathione which is considered a master antioxidant can help keep the balance between the oxidant and antioxidant system in the body and prove to be an effective therapy but studies proving its efficacy are limited

X., Bos, P

Y., and Shang, P

Standard Dosing Range Most research and user protocols fall within 0.1 to 0.3 mg per injection

Arch Facial Plast Surg

One subject experienced mild erythema on Days 2 and 3, which resolved by Day 4 without discontinuing the lotion