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As a result, the antioxidant system is crucial to prevent any influence caused by ROS overproduction ( via an AMPK-dependent pathway

For example, if you have a gastrointestinal disorder that affects nutrient absorption, or if you follow a vegan or vegetarian diet, you may be at higher risk of developing a deficiency and may require supplementation

The non-protein amino acid BMAA is misincorporated into human proteins in place of l-serine causing protein misfolding and aggregation

LAMPs were originally believed just to be structural proteins that protect lysosomal membrane from resident hydrolytic enzymes, although evidence now reveals that they have a key physiological role in suppressing proton leak through TMEM175 channels to facilitate re-acidification when lysosomal pH rises inappropriately 96

doi: 10.1038/s41467-021-24347-7 87 VonderheideRH