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The molecule was developed by Frank Ng's group at Monash University and Metabolic Pharmaceuticals in Australia during the 1990s and 2000s as a potential anti-obesity drug intended to isolate the lipolytic region of hGH without activating the growth hormone receptor or raising IGF-1.nnIn published preclinical work, the fragment has been shown to stimulate lipolysis, suppress lipogenesis, and modulate the beta-3 adrenergic receptor pathway in adipose tissue rather than acting through the classical hGH receptor

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Several GDF-15 agonists are undergoing early phase clinical trials including NNC0247-0829 and JNJ-9090/CIN-109

PubChem Reference: View compound profile on NIH PubChem Key Characteristics MOLECULAR PROFILE Formula: C 14 H 22 N 4 O 9 Weight: 390.34 g/mol CAS: 307297-39-8 Structure: Ala-Glu-Asp-Gly PHYSICAL PROPERTIES Form: White lyophilized powder Solubility: Readily dissolves in water Origin: Synthetic version of epithalamin Storage: Keep refrigerated 3646 F (28 C) Related products BPC-157 $40.00 $65.00Price range: $40.00 through $65.00 NAD+ $40.00 $125.00Price range: $40.00 through $125.00

If youre interested, Synedica has a product that has the two compounds combined, making the dual-peptide formulation process easier