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Less frequent sessions may be more effective Finding: Reducing microneedling session frequency (e.g., fortnightly rather than weekly) showed a positive influence on treatment outcomes

U.KimE.et al (2022)

In preclinical research models, exposure to GHK-Cu has been associated with altered gene expression patterns and modulation of signalling pathways related to extracellular matrix dynamics, oxidative stress response, and cellular turnover

This may directly affect gene transcription or recruit transcription factors to specific promoter regions

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The strongest clinical use cases are metabolic slowdown, fatigue, exercise intolerance, insulin resistance, and visceral fat in patients who have plateaued with diet and training alone