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Microglial replacement using Ki20227, a CSF1R inhibitor, in 2HIT mice restored behaviors resembling psychiatric disorders, suggesting a causal contribution of 2HIT stress-reactive microglia, including SAM (Hikosaka et al., 2025)

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Early clinical care helps prevent scarring

They're all downstream of the same underlying cellular environment

Pediatric patients have two relevant characteristics, among others, to be considered when immunotherapies are applied: 1- the immune response in these patients can be different from an adult