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Lipoxygenases (LOXs) are considered one of the central players in ferroptosis (Ayala et al., 2014)

Enhanced functional recovery from spinal cord injury in aged mice after stem cell transplantation through HGF induction

It seems however, (at least based on a limited number of studies) that degeneration, loss of function, dysregulated metabolism, impaired second messenger signalling and death of astrocytes are predominant pathophysiological manifestations

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Like any other organ, the brain is vascularized from the surrounding vascular plexus during embryogenesis, and the BBB is tempered by the bodys immune system from embryonic development [513]

11 , eaaq0702 (2018)