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Studies have shown that supplementing cobalamin in deficient cats experiencing gastrointestinal disease, like vomiting and diarrhea, has led to a significant improvement in GI signs, as well as weight gain

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Changes in vision In extreme cases, a lack of B12 may damage the optic nerve or plug up the blood vessels in the retina, causing blurry vision, double vision, sensitivity to light, and even vision loss, per research in Cureus