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An expanded search of the references and related literature was carried out to avoid omission

The key characteristics of nephrosclerosis encompass focal and global glomerulosclerosis, tubular atrophy, interstitial fibrosis, and arteriosclerosis

These diseases typically involve chronic inflammation, oxidative stress, mitochondrial dysfunction, impaired protein clearance, and gradual loss of neuron structure and function, leading to cognitive, motor, and sensory impairments depending on the area of the nervous system that is affected

Notably, glucobrassicin generally represents 814% of the total glucosinolates in edible parts

Although PIs represent a highly effective anti-myeloma therapy and transformed the management of MM, drug resistance inevitably emerges through compensatory protein clearance mechanisms, e.g., the aggresome+autophagy pathway (34)

The Role of Glutathione in the Body Antioxidant Defense : Glutathione helps combat oxidative stress by scavenging free radicals, which can damage cellular structures, including DNA, proteins, and lipids