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Other GlyT1 inhibitors Currently, several studies are focused on the identification and characterization of novel GlyT1 inhibitors, such as Amgens benzhydryl piperazine AMG 747, Organons Org25935 and Org24461, NPTS, ASP2535, CP-802,079, PF-03463275, SSR504734, LY2365109, and BI 425809

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Consistent with this function of ERK1/2, treatment with ebselen, a GPx mimetic and antioxidant, decreased ERK1/2 activation as well as the rate of macrophage cell proliferation [80]