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A change in promoter methylation of hMLH1 is a cause of acquired resistance to platinum-based chemotherapy in epithelial ovarian cancer

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Experimental nonalcoholic steatohepatitis and liver fibrosis are ameliorated by Pharmacologic activation of Nrf2 (NF-E2 p45-related factor 2)

In addition to the role of autophagy in mediating DOX resistance, other aspects that can be considered include the interplay between the TME and drug response, as factors such as hypoxia, stromal interactions, and immune modulation may affect both autophagy and chemoresistance