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For instance, Curcumin has been shown to covalently bind to the Cys151 residue of KEAP1, thereby stabilizing NRF2 and enhancing antioxidant effects

(2005) A multicenter phase II trial of ZD6474, a vascular endothelial growth factor receptor-2 and epidermal growth factor receptor tyrosine kinase inhibitor, in patients with previously treated metastatic breast cancer

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The acquired resistance aligned with decreases in cell proliferation and in the extent of lipid peroxidation, as well as with an increase in the expression of GPX4 upon differentiation

l , Excitatory postsynaptic current (EPSC) frequency

Acknowledgements The authors thank Conselho Nacional de Pesquisa e Tecnologia (CNPq) and Fundao de Amparo Pesquisa do Estado de So Paulo (FAPESP)