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73 Three categories of chemical modifications are manifested in rRNA: ribose methylation (Nm), the isomerization of uridine to pseudouridine (), along with base modifications such as methylation (mN), acetylation (acN), and aminocarboxypropylation (acpN)

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Consequently, when calculating the volumes of the cavities using the program CASTp with a probe radius of 3 48 , the apo conformation had a cavity volume of ~4883 3 , while the substrate-bound forms exhibited much smaller cavity volumes ranging from 2312 to 2613 3 (Fig

Previous studies have shown that GLP-1 can inhibit the formation and progression of NAFLD by enhancing lipid metabolism through oxidation and reducing the influx of fatty acids into hepatocytes [104]