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While not risk-free, evidence suggests e-cigarettes provide harm reduction

Risk factors for lung cancer worldwide

Once it was discovered that the main ingredient in tobacco, nicotine, is poisonous, the practice began to lose favour during the early 19th century In the 16th century, tobacco came to Europe simply as a plant under the nightshade family, which tomatoes, aubergines and peppers also fall under

Smaller packs might encourage smokers to moderate their consumption, while larger packs could potentially lead to increased smoking due to the availability of more cigarettes

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