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Local and global influences on protein turnover in neurons and glia

doi: 10.1038/nrc.2018.6 46 ZaorskyNGHarrisonASTrabulsiEJGomellaLGShowalterTNHurwitzMDet al

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These designs allow for pre-specified modifications, such as dose adjustments, reallocation of participants, or sample size recalibration, based on interim data, without compromising statistical rigor