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[DOI] [PMC free article] [PubMed] [Google Scholar] Lander, S

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Elevated intra-articular iron levels and altered expression of ferroptosis-related molecules such as ACSL4 and GPX4 have been associated with the severity of joint pain, cartilage damage, and functional decline ( In summary, ferroptosis is a shared pathological mechanism across multiple joint tissues in OA

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While vitamin B12 deficiency can lead to the underdevelopment of the brain in early life, it can also lead to severe symptoms in adulthood, ranging from dementia, memory loss and cognitive/intellectual decline